Employing single-molecule optical and AFM imaging and force-spectroscopy approaches, we search for to unravel the mechanistic areas of the construction and dynamics of chromosomes. Our study pursuits include things like:
You regularly get entangled in discussions about science and faith. You've also penned many books on the subject. Don’t you believe eventually we will know anything and that God’s purpose will likely be around?
Dynamics of initiation, termination and reinitiation of DNA translocation with the motor protein EcoR124I
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
This yielded a breakthrough. In just only some months, we had been able to measure transportation by way of an individual solitary-walled carbon nanotube. Based on lower-temperature experiments by a brilliant PhD scholar in my group, Sander Tans (now a valued colleague and professor at Delft University of Technology using an Lively analysis lab at AMOLF in Amsterdam), we confirmed that carbon nanotubes had been authentic quantum wires with extremely prolonged (micrometres) electronic coherence lengths — confirming theoretical predictions of metallic conduct.
Experimental period diagram of negatively supercoiled DNA measured by magnetic tweezers and fluorescence,
You're a Christian. If you might make such a artificial cell, would you be just one phase nearer to God, or would the position of God have diminished relatively all over again?
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Presently, we also understood that it ought to be attainable to work with an individual semiconducting carbon nanotube to produce a transistor — and we set out to make it. We stretched individual semiconducting nanotubes throughout metallic electrodes and applied the fundamental silicon substrate being a gate electrode, setting up The fundamental three-terminal layout of the discipline-result transistor (Fig.
FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in bacterial cell division
2006, 1st demonstration of molecular sorting in a lab on the chip employing biomotors; discovery of nanobubbles in good-state nanopores; and very first estimate of electrokinetic Electricity conversion in a nanofluidic channel
Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of one wire bridging two electrodes
Finally, I will briefly sketch a few of our Concepts to check out the making of artificial cells, precisely our to start with steps ceesdekker.net to determine artificial mobile division.